Cremophor EL-40
CAS No. : 61791-12-6
(Synonyms: Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil)
| Size | Price | Stock |
|---|---|---|
| 100 mL | $80 | In-stock |
| 200 mL | $128 | In-stock |
| 500 mL | $240 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-Y1890 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic);Ethanol : 50 mg/mL (ultrasonic) |
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents[1].
In Vitro:Cremophor EL-40 is a widely used excipient. In the first 10 h, Cremophor EL-40 at 5 mg/mL increases the impedance, then decreases it, and after 20 h of treatment, epithelial cell death is detected. Cremophor EL-40 decreases cell viability and increases cell toxicity more than RH40. Both epithelial viability and monolayer integrity are seriously impaired at 10 to 50 mg/mL concentrations of Cremophor EL-40 at 24-h treatment. Cremophor EL-40 also enhances cell detachment[1].
Note:
Due to the nature of the product, it may solidify after being stored at 4℃. It can be heated in a 37℃ water bath before use. It can be used normally after it is completely dissolved.
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