OMDM-2


CAS No. : 616884-63-0

616884-63-0
Price and Availability of CAS No. : 616884-63-0
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Cat. No. : HY-103342
M.Wt: 431.65
Formula: C27H45NO3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 616884-63-0 :

OMDM-2 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 3.0 μM[1]. IC50 & Target:Ki: 3.0 μM (anandamide cellular uptake)[1] In Vitro: OMDM-2 shows poor affinity for either CB1 (Ki=5.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively; OMDM-2 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50=10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1].

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