Vasicine
CAS No. : 6159-55-3
(Synonyms: Peganine)
| Size | Price | Stock |
|---|---|---|
| 5mg | $160 | In-stock |
| 10mg | $260 | In-stock |
| 25mg | $500 | In-stock |
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| Cat. No. : | HY-N1103 |
| M.Wt: | 188.23 |
| Formula: | C11H12N2O |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic) |
Vasicine (peganine) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine activates PI3K/Akt signaling pathway, exhibits antioxidant, anti-inflammatory and antibacterial activities[1][2][3]. In Vitro:Vasicine (10-100 μg/mL, 10 min) exhibits a moderate inhibitory activity against H+/K+-ATPase (IC50=73.47 μg/mL), scavenges DPPH free radical (IC50=71.97 μg/mL), reduces gastric acid secretion and exhibits anti-ulcer effect[3]. In Vivo:Vasicine (2.5-10 mg/kg, po, once daily for 7 days) improves the cardiac function, inhibits myocardial cell apoptosis, and alleviates myocardial necrosis, edema, and inflammatory cell infiltration in Isoproterenol (HY-B0468)-induced rats myocardial infarction models[2].
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