Quercetin (dihydrate)
CAS No. : 6151-25-3
| Size | Price | Stock |
|---|---|---|
| 500mg | $55 | In-stock |
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| 5 g | Get quote | |
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| Cat. No. : | HY-N0146 |
| M.Wt: | 338.27 |
| Formula: | C15H14O9 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1]. IC50 & Target: IC50:PI3K γ (2.4 μM)，PI3K δ (3.0 μM)，PI3K β (5.4 μM)(Quercetin dihydrate)[1] In Vitro: Quercetin dihydrate is a type of plant-based chemical, or phytochemical, used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits[1].Quercetin dihydrate is a PI3K inhibitor with IC50s of 2.4-5.4 μM. Quercetin dihydrate strongly abrogates PI3K and Src kinases, mildly inhibits Akt1/2, and slightly affected PKC, p38 and ERK1/2[1].Quercetin dihydrate inhibits TNF-induced LDH% release, EC-dependent neutrophils adhesion to bovine pulmonary artery endothelial cells (BPAEC), and BPAEC DNA synthesis and proliferation[2].
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