5-Nitroindole


CAS No. : 6146-52-7

6146-52-7
Price and Availability of CAS No. : 6146-52-7
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10g $16 In-stock
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Cat. No. : HY-59273
M.Wt: 162.15
Formula: C8H6N2O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 6146-52-7 :

5-Nitroindole is a mutagenic nitroarene and universal base analog. 5-Nitroindole significantly reduces the cellular adenylate energy charge by decreasing ATP levels and increasing AMP levels. 5-Nitroindole inhibits lipid peroxidation[1][2]. In Vitro:5-Nitroindole (25-100 μM; 0-4 h) decreases the adenylate energy charge of rat hepatocytes significantly by reducing ATP levels and increasing AMP levels[1].
5-Nitroindole (50-100 μM; 15-60 min) inhibits NADPH-dependent and t-BuOOH-dependent lipid peroxidation in liver microsomes, and NADH-initiated lipid peroxidation in mitochondria[1].

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