Closantel (sodium)
CAS No. : 61438-64-0
| Size | Price | Stock |
|---|---|---|
| 500mg | $8 | In-stock |
| 100g | $79 | In-stock |
| 500g | $259 | In-stock |
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| Cat. No. : | HY-17596A |
| M.Wt: | 685.06 |
| Formula: | C22H13Cl2I2N2NaO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing[1][2].
In Vitro: Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase[1].
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