Oxythiamine (chloride hydrochloride)
CAS No. : 614-05-1
(Synonyms: Hydroxythiamine (chloride hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 50mg | $40 | In-stock |
| 100mg | $60 | In-stock |
| 250mg | $84 | In-stock |
| 500mg | $100 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-107430A |
| M.Wt: | 338.25 |
| Formula: | C12H17Cl2N3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Oxythiamine (Hydroxythiamine) chloride hydrochloride, an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine chloride hydrochloride is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine chloride hydrochloride inhibits cancer cell apoptosis and inhibits cell proliferation[1][2][3].
IC50 & Target:Vitamin B1, Thiamine, Transketolase[1].
In Vitro: Oxythiamine chloride hydrochloride (0-40 μM, 2 days) inhibits cell viability of MIA PaCa-2 cells (IC50: 14.95 μM)[1].
Oxythiamine chloride hydrochloride (0-500 μM, 48 h) suppresses expression of 14-3-3 protein beta/alpha in MIA PaCa-2 cells[1].
Oxythiamine chloride hydrochloride (0.1-100 μM, 6-48 h) inhibits A549 cell proliferation[3].
Oxythiamine chloride hydrochloride (0.1-100 μM, 24 h) induces A549 cell apoptosis[3].
Oxythiamine chloride hydrochloride (0–20 μM) inhibits the invasion and migration (IC50: 8.75 μM) of Lewis lung carcinoma (LLC) cells[4].
In Vivo: Oxythiamine chloride hydrochloride (100-500 mg/kg, i.p. 4 days) inhibits tumor growth in Ehrlich's ascites tumor hosting mice[2].
Oxythiamine chloride hydrochloride (250 or 500 mg/kg, daily for 5 week) inhibits tumor cell metastasis via inhibition of MMPs in mice implanted (s.c.) with LLC cells[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Oxythiamine (chloride hydrochloride)
- Cat. No.:
- HY-107430A
- Quantity:
Your information is safe with us.