Rifapentine


CAS No. : 61379-65-5

(Synonyms: DL 473; Cyclopentylrifampicin)

61379-65-5
Price and Availability of CAS No. : 61379-65-5
Size Price Stock
50mg $77 In-stock
100mg $132 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-B0269
M.Wt: 877.03
Formula: C47H64N4O12
Purity: >98 %
Solubility: DMSO : ≥ 50 mg/mL;H2O : < 0.1 mg/mL
Introduction of 61379-65-5 :

Rifapentine (DL 473) is an antibiotic used in tuberculosis research[1]. In Vitro:Rifapentine shows antibacterial activity against clinical staphylococci, with MICs ranging from 0.002 to >10 μg/mL (MIC90 values of 1.28 μg/mL for MSSA and MSSE, and ≥10 μg/mL for MRSA and MRSE)[3].
In Vivo:Rifapentine (20 mg/kg, i.p., daily for five days followed by twice weekly for three weeks) reduces bacteria burden in the organs of a mouse model of disseminated Mycobacterium avium infection[2].
Rifapentine (a single dose of 30 mg/kg, i.v.) shows a plasma Cmax, T1/2 and AUC0-15 were 33 µg/mL (0.5 h), 4 h and 170 µg h/mL in rabbits. In lung tissue, the Cmax, T1/2 and AUC0-15 are 13 µg/mL (2 h), 6.7 h and 82 µg h/mL[4].

Your information is safe with us.