| Size | Price | Stock |
|---|---|---|
| 50mg | $77 | In-stock |
| 100mg | $132 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-B0269 |
| M.Wt: | 877.03 |
| Formula: | C47H64N4O12 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL;H2O : < 0.1 mg/mL |
Rifapentine (DL 473) is an antibiotic used in tuberculosis research[1].
In Vitro:Rifapentine shows antibacterial activity against clinical staphylococci, with MICs ranging from 0.002 to >10 μg/mL (MIC90 values of 1.28 μg/mL for MSSA and MSSE, and ≥10 μg/mL for MRSA and MRSE)[3].
In Vivo:Rifapentine (20 mg/kg, i.p., daily for five days followed by twice weekly for three weeks) reduces bacteria burden in the organs of a mouse model of disseminated Mycobacterium avium infection[2].
Rifapentine (a single dose of 30 mg/kg, i.v.) shows a plasma Cmax, T1/2 and AUC0-15 were 33 µg/mL (0.5 h), 4 h and 170 µg h/mL in rabbits. In lung tissue, the Cmax, T1/2 and AUC0-15 are 13 µg/mL (2 h), 6.7 h and 82 µg h/mL[4].
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