1-Methylxanthine
CAS No. : 6136-37-4
| Size | Price | Stock |
|---|---|---|
| 100mg | $43 | In-stock |
| 250mg | $53 | In-stock |
| 1g | $135 | In-stock |
| 5g | $540 | In-stock |
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| 50 g | Get quote | |
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| Cat. No. : | HY-W008449 |
| M.Wt: | 166.14 |
| Formula: | C6H6N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].
In Vitro: 1-Methylxanthine (1-MTX; 3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death[2].
1-Methylxanthine (1MX) exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine, TP, and theobromine, 3-Methylxanthine (3MX) and 1-methylxanthine do not occur naturally at high levels in plants[1].
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