GW 848687X
CAS No. : 612831-24-0
| Size | Price | Stock |
|---|---|---|
| 500μg | $196 | Get quote |
| 1mg | $370 | Get quote |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
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| Cat. No. : | HY-14466 |
| M.Wt: | 441.85 |
| Formula: | C24H18ClF2NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GW 848687X is a selective, orally active prostaglandin EP1 receptor antagonist for the inhibition of inflammatory pain. The oral bioavailability of GW 848687X was 54% in rats and 53% in dogs. GW 848687X has a half-life of 2 hours and has inhibitory potential for both acute and chronic pain[1].
In Vivo:GW 848687X (30 mg/kg; po; b.i.d, 5 d) exhibits antihyperalgesic activity in an FCA-induced inflammatory joint pain model[1].
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