JY-XHe-053


CAS No. : 612526-36-0

612526-36-0
Price and Availability of CAS No. : 612526-36-0
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Cat. No. : HY-123426
M.Wt: 373.38
Formula: C22H16FN3O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 612526-36-0 :

JY-XHe-053 is a potent and selective agonist of GABAA receptors containing the α5 subunit (Kis of 22.0 nM, 12.3 nM, 34.9 nM, 0.7 nM for α1, α2, α3, α5, respectively). JY-XHe-053 lacks significant anti-anxiety activity, despite its efficacy at α2- and α3-GABAA receptors[1][2].

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