L-Glutamic acid (monosodium) (hydrate)
CAS No. : 6106-04-3
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|---|---|---|
| 1000g | $53 | In-stock |
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| Cat. No. : | HY-W016145 |
| M.Wt: | 187.13 |
| Formula: | C5H10NNaO5 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors[1][2][3][4][5].
In Vitro: L-Glutamic acid (120-1000 mg/dL) monosodium hydrate can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus[3].
L-Glutamic acid (2-20 mM, 24-48 h) monosodium hydrate can induce neuroexcitotoxicity in neuroblastoma[4].
In Vivo: L-Glutamic acid (3 g/kg, subcutaneous injection, single dose) monosodium hydrate can promote excitotoxic degeneration of retinal ganglion cells in mice[1].
L-Glutamic acid (750 mg/kg, intraperitoneal injection) monosodium hydrate can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats[5].
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