2,3,4-Trihydroxybenzoic acid
CAS No. : 610-02-6
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| 500g | $190 | In-stock |
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| Cat. No. : | HY-W016993 |
| M.Wt: | 170.12 |
| Formula: | C7H6O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
2,3,4-Trihydroxybenzoic acid is an α-amylase inhibitor with an IC50 of 17.30 mM against porcine α-amylase. 2,3,4-Trihydroxybenzoic acid increases cellular p21 and p27 protein levels. 2,3,4-Trihydroxybenzoic acid inhibits cancer cell growth and delays starch digestion to suppress postprandial hyperglycemia. 2,3,4-Trihydroxybenzoic acid can be used in research related to colorectal cancer, breast cancer and type 2 diabetes[1][2].
In Vitro:2,3,4-Trihydroxybenzoic acid (24-72 h) inhibits the proliferation of HCT-116 colon cancer cells in vitro[1].
2,3,4-Trihydroxybenzoic acid inhibits colony formation of HCT-116 colon cancer cells in vitro[1].
2,3,4-Trihydroxybenzoic acid inhibits colony formation of MDA-MB-231 breast cancer cells in vitro, and MDA-MB-231 cells are more sensitive than HCT-116 colon cancer cells[1].
2,3,4-Trihydroxybenzoic acid increases the protein levels of p21 and p27 in HCT-116 colon cancer cells[1].
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