| Size | Price | Stock |
|---|---|---|
| 5g | $10 | In-stock |
| 25g | $15 | In-stock |
| 100g | $40 | In-stock |
| 500g | $150 | Get quote |
| 1000g | $250 | Get quote |
| > 2 kg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-B0574 |
| M.Wt: | 241.29 |
| Formula: | C15H15NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic) |
Mefenamic acid is a BBB-permeable and non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. IC50 & Target:IC50: 40 nM (hCOX-1), 3 μM (hCOX-2)[1] In Vitro:Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively[1]. Mefenamic acid (0-100 μM) has cytotoxic effects on KB, Saos-2, and 1321N cells, however, U-87MG cells are resistant to Mefenamic acid[2].
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