Meloside A
CAS No. : 60767-80-8
(Synonyms: Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside)
| Size | Price | Stock |
|---|---|---|
| 5mg | $330 | In-stock |
| 10mg | $500 | In-stock |
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| Cat. No. : | HY-N5124 |
| M.Wt: | 594.52 |
| Formula: | C27H30O15 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid found in barley with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss[1].
In Vitro:Meloside A (5-100 μg/mL, 24 h) does not induce significant cytotoxicity in HDPCs[1].
Meloside A (50-100 μg/mL, 6-24 h) inhibits DHT-induced AR nuclear translocation and AR protein expression in HDPCs[1].
Meloside A (100 μg/mL, 24 h) reduces ROS levels in DHT-induced HDPCs[1].
Meloside A (50-100 μg/mL, 48 h) reduces the secretion of DKK-1, IL-6, and TGF-β1 in DHT-induced HDPCs[1].
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