NADH (disodium salt)
CAS No. : 606-68-8
(Synonyms: Disodium NADH)
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
| 500mg | $60 | In-stock |
| 1g | $70 | In-stock |
| 5g | $210 | In-stock |
| 10g | $315 | In-stock |
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| Cat. No. : | HY-F0001 |
| M.Wt: | 709.40 |
| Formula: | C21H27N7Na2O14P2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL;DMSO : 100 mg/mL (ultrasonic) |
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle[1].
In Vitro: NADH is unstable under acidic conditions but it is stable under alkaline conditions[2].
NADH (0-1 mM; 0-12 h) increases NAD+ levels in various mammalian cell lines[3].
NADH (1 mM; 24 h) causes low toxicity and protects cells from genotoxicity[3].
In Vivo: NADH (5 μmol/mouse; i.p.; once) increases urinary excretion of nicotinamide and its metabolites in mice[2].
NADH (500 mg/kg; i.g.; once) promotes alcohol metabolism and prevents or ameliorates early liver injury caused by acute alcohol exposure in ethanol-loaded mice[3].
NADH (1000 mg/kg; i.p.; once) enhances tissue NAD+ levels in male C57BL/6J mice[3].
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