Creatine (monohydrate)
CAS No. : 6020-87-7
| Size | Price | Stock |
|---|---|---|
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| 1000g | $255 | Get quote |
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| Cat. No. : | HY-W017462 |
| M.Wt: | 149.15 |
| Formula: | C4H11N3O3 |
| Purity: | >98 % |
| Solubility: | H2O : 16.67 mg/mL (ultrasonic) |
Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].
In Vitro:Creatine monohydrate (10-20 mM, 1-3 weeks) promotes the cell growth, differentiation and mineralization of osteoblast-like cells[2].
Creatine monohydrate (0.1-10 mM, 2-24 h) scanvages the free radicals, protects the DNA especially mtDNA from oxidative damage[3].
In Vivo:Creatine monohydrate (0.1-1000 mg/kg, po, single dose) exhibits antidepressant-like activity in mouse tail suspension test, which could be enhanced by dopamine receptor agonist SKF38393 (HY-12520A) and Apomorphine (HY-12723)[4].
Creatine monohydrate (0.03-0.3 mg/kg, drinking water for 8 weeks) stimulates the PI3K/AKT signaling pathways, promotes the protein synthesis and muscle hypertrophy, thereby promoting the performance of short-duration, high-intensity exercise in rats models[5].
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