Cetylpyridinium (chloride monohydrate)
CAS No. : 6004-24-6
(Synonyms: Hexadecylpyridinium chloride monohydrate)
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| Cat. No. : | HY-B1289 |
| M.Wt: | 358.00 |
| Formula: | C21H40ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, and throat and nasal sprays as an antiseptic that kills bacteria and other microorganisms. Effectively prevents plaque and reduces gingivitis. In Vitro:Cetylpyridinium chloride monohydrate (7.5-50 µg/mL, 5 minutes) disrupts the influenza viral envelope in a dose-dependent manner, leading to structural damage, increased membrane permeability, and nucleoprotein release[2]. Cetylpyridinium chloride monohydrate (10-250 µg/mL, 48 hours) exhibits dose-dependent cytotoxicity in MDCK cells, with a CC50 of 96 µg/mL[2]. In Vivo:Cetylpyridinium chloride monohydrate (5 µL of 0.1% Cetylpyridinium chloride monohydrate, p.o., twice daily for 5 days) enhances survival and reduces influenza-associated morbidity and mortality in C57BL/6 mice infected with mouse-adapted Influenza A (PR8 strain)[2].
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