6-Aminocaproic acid
CAS No. : 60-32-2
(Synonyms: EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid)
| Size | Price | Stock |
|---|---|---|
| 100g | $15 | In-stock |
| 500g | $69 | In-stock |
| 1000g | $121 | In-stock |
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| Cat. No. : | HY-B0236 |
| M.Wt: | 131.17 |
| Formula: | C6H13NO2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL;DMSO : < 1 mg/mL |
6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
In Vitro: 6-Aminocaproic acid (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL[2].
6-Aminocaproic acid can be used as a hydrophobic linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green[4].
In Vivo: 6-Aminocaproic acid (20-100 mg/kg; a single p.o.) inhibits fibrinolysis at all doses tested in dogs[3].
6-Aminocaproic acid (20-100 mg/kg; a single p.o.) is rapidly absorbed (Tmax=1 h) and eliminated rapidly in dogs[3].
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