NSC243928 (mesylate)


CAS No. : 59988-01-1

59988-01-1
Price and Availability of CAS No. : 59988-01-1
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10mg $650 In-stock
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Cat. No. : HY-123885
M.Wt: 503.59
Formula: C23H25N3O6S2
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 59988-01-1 :

NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1]. In Vitro:NSC243928 mesylate (2 μM, 24 h) induced cell death in MDA-MB-231 control cells and showed an increase in cell viability in LY6K knockdown cells, thus suggesting that NSC243928 may induce cell death through the LY6K pathway[1].
NSC243928 mesylate inhibits MDA-MB-231, Hs-578-T, BT-549 and OVCAR-8 cells with the IC50 values of 5.683 μM, 7.309 μM, 7.954 μM and 4.167 μM, respectively[1].

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