Patchouli alcohol
CAS No. : 5986-55-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $35 | In-stock |
| 25mg | $70 | In-stock |
| 50mg | $115 | In-stock |
| 100mg | $185 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-N0207 |
| M.Wt: | 222.37 |
| Formula: | C15H26O |
| Purity: | >98 % |
| Solubility: | Ethanol : 20 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic) |
Patchouli alcohol is a natural tricyclic sesquiterpene, exhibits anti-Helicobacter pylori, anti-inflammatory and antioxidant properties[1]. In Vitro:Patchouli alcohol (5-20 μg/mL; 24 h) not only significantly increases the cell viability and decreased cellular lactate dehydrogenase (LDH) leakage, but also markedly elevates the mitochondrial membrane potential and remarkably attenuated GES-1 cellular apoptosis, thereby protecting gastric epithelial cells against injuries caused by H. pylori. Patchouli alcohol also inhibits the secretions of pro-inflammatory factors, such as MCP-1, TNF-α and IL-6[1]. In Vivo:Patchouli alcohol (5-20 mg/kg; oral administration; for 2 weeks) significantly protects the gastric mucosa from H. pylori-induced damage. Patchouli alcohol effectively attenuates oxidative stress by decreasing contents of intracellular ROS and MDA, and increasing levels of NP-SH, GSH/GSSG. Patchouli alcohol significantly attenuates the secretions of IL-1β, keratinocyte chemoattractant and IL-6[1].
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