Diethyl phosphate


CAS No. : 598-02-7

(Synonyms: Diethyl phosphoric acid)

598-02-7
Price and Availability of CAS No. : 598-02-7
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Cat. No. : HY-101417
M.Wt: 154.10
Formula: C4H11O4P
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 598-02-7 :

Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats[1][2][3]. In Vitro: Diethyl phosphate can interact with thyroid hormone biosynthesis, blood transport, receptor binding and metabolism-related enzymes/proteins, interfering with the production and signal regulation of thyroid hormones in silico[1]. In Vivo: Diethyl phosphate (oral gavage; 0.08-0.8 mg/kg; 24 weeks) can lead to the disturbance of endocrine hormones and related metabolic indexes in rats[1].
Diethyl phosphate (oral gavage; 0.08-0.13 mg/kg; 20 weeks) affects the intestinal microbiota, serum hormones and pro-inflammatory cytokines[2].

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