Cyclosporin C
CAS No. : 59787-61-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $60 | In-stock |
| 5mg | $130 | In-stock |
| 10mg | $210 | In-stock |
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| Cat. No. : | HY-N6027 |
| M.Wt: | 1218.61 |
| Formula: | C62H111N11O13 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C shows no activity against bacteria or yeasts[1][2][3].
In Vitro:Cyclosporin C is active against isolates of Fusarium fumigatum, Aspergillus Niger, Cyclospora, Mucor and Penicillium (MICs = 0.1-5 μg/mL)[1].
Cyclosporin C (15 μg/mL) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%[2].
Cyclosporin C (100 ng/mL) inhibits lymphocyte proliferation induced by the mitogens concanavalin A (HY-P2149), phytohemagglutinin L (HY-N7038), and pokeweed mitogen (HY-NP187)[3].
In Vivo:Cyclosporin C (100 ng/mL, once) inhibits the local graft-versus-host (GVH) reaction in mice receiving splenocyte grafts[3].
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