CAY10410


CAS No. : 596104-94-8

(Synonyms: 11-Oxo-prosta-5Z,12E,14Z-trien-1-oic acid)

596104-94-8
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Cat. No. : HY-117422
M.Wt: 318.45
Formula: C20H30O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 596104-94-8 :

CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes[1]. In Vitro:CAY10410 (11-Oxo-prosta-5Z; 1 μM; 24 h) activates PPRE-LUC activity and this activation is inhibited by the PPARγ DN in B cells[1].
CAY10410 (0-25 μM; 48 h) does not inhibit either Ramos cells or normal human B cells, even at doses up to 25 μM[1].

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