Megestrol acetate


CAS No. : 595-33-5

595-33-5
Price and Availability of CAS No. : 595-33-5
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500mg $55 In-stock
1g $73 In-stock
5g $222 In-stock
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Cat. No. : HY-13676
M.Wt: 384.51
Formula: C24H32O4
Purity: >98 %
Solubility: DMSO : 20 mg/mL (ultrasonic)
Introduction of 595-33-5 :

Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway[1][2][3][4][5].
In Vitro: Megestrol acetate alone results in an ICKY of 48.7 p,M in the MCF7/ADR cell line[2].
In Vivo: Megestrol acetate (100 or 300 mg/kg, Subcutaneously daily over a 7-day period) is able to reduce the weight loss produced by both TNF and by the MAC16 tumour[1].

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