Soyasapogenol B
CAS No. : 595-15-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $190 | In-stock |
| 10mg | $300 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N6074 |
| M.Wt: | 458.72 |
| Formula: | C30H50O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C) |
Soyasapogenol B is a component of soy that has oral activity. Soyasapogenol B promotes autophagy and apoptosis. Soyasapogenol B has anti-inflammatory, antioxidant and antitumor activities[1][2][3].
In Vitro:Soyasapogenol B (5-20 μM, 48 h) can reduce tumor cell viability and promote apoptosis and autophagy of colorectal cancer cells through endoplasmic reticulum stress[1].
Sovasapogenol B (1-10 μM, 48 h) shows anti-growth and anti-metastasis activity in clear cell renal cell carcinoma (ccRCC)[2].
In Vivo:Soyasapogenol B (25 or 50 mg/kg/day, intraperitoneal injection) can inhibit tumor growth, and promote apoptosis and autophagy in a mouse tumor model of colorectal cancer[1].
Soyasapogenol B (10 mg/kg, oral) alleviates memory impairment induced by lipopolysaccharide (HY-D1056) in mice by regulating the expression of BDNF mediated by NF-κB[3].
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