1-Methyl-2-undecyl-4(1H)-quinolone
CAS No. : 59443-02-6
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| Cat. No. : | HY-N1638 |
| M.Wt: | 313.48 |
| Formula: | C21H31NO |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2].
IC50 & Target: IC50: 15.3 μM (MAO-B)[2].
Ki: 9.91μM (MAO-B)[2]
In Vitro: 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity[2].
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