ON 01500
CAS No. : 592542-50-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $125 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $360 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-78883 |
| M.Wt: | 393.45 |
| Formula: | C19H23NO6S |
| Purity: | >98 % |
| Solubility: |
ON 01500 is a tubulin inhibitor with a Kd of 21 nM. ON 01500 exerts microtubule-destabilizing effects in cells. ON 01500 can be used the study of cancers[1][2].
In Vitro:ON 01500 (1 μM) completely inhibits tubulin polymerization in MAP-rich tubulin samples[1].
ON 01500 (7-15 nM, 3-5 days) sensitizes cells to knockdown of TACC3 or overexpression of KIF2C and protects cells from overexpression of TACC3 or knockdown of KIF2C, with high toxicity[2].
ON 01500 (10 nM, 3-7 days) induces enrichment of L240F TUBB-expressing (mCherry-positive) K562 cells relative to wild-type cells[2].
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