Sulforaphene
CAS No. : 592-95-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $220 | In-stock |
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| Cat. No. : | HY-N2450 |
| M.Wt: | 175.27 |
| Formula: | C6H9NOS2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals[1][2][3][4].
In Vitro:Sulforaphene (0-80 μM, 48 h) inhibits HCC (HepG2 and Hep3B cells) cell viability and induces apoptosis[4].
Sulforaphene (0-40 μM) sensitizes radiosensitivity of HepG2 and Hep3B cells, and promotes radiation-induced cell death[4].
Sulforaphene (0-10 μM, 24 h) inhibits SUM159 cell migration and invasion by inhibiting Hedgehog signaling[5].
Sulforaphene (5 μM, 24 h) inhibits microtubule polymerization in HCT116 and HT-29 cells[6].
In Vivo:Sulforaphene (1 and 5 mg/kg, i.p., everyday) inhibits tumor growth in a mouse HCT116 xenograft model[6].
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