Niacin


CAS No. : 59-67-6

(Synonyms: Nicotinic acid; Vitamin B3)

59-67-6
Price and Availability of CAS No. : 59-67-6
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500mg $55 In-stock
1g $66 In-stock
5g $86 In-stock
10g $127 In-stock
25g $210 In-stock
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Cat. No. : HY-B0143
M.Wt: 123.11
Formula: C6H5NO2
Purity: >98 %
Solubility: H2O : 10 mg/mL (ultrasonic);DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 59-67-6 :

Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2]. In Vitro: Niacin (0-900 μM, 42 hours) significantly increases GSH levels and decreases ROS levels, and affects the expression of genes related to apoptosis and lipid metabolism[1].
Niacin (0-40 μM, 24 hours) can inhibit cancer invasive activity at low dose but with no influence on proliferation[2].
In Vivo: Niacin (subcutaneous injection, 3-300 mg/kg, once) can induce vasodilation in a dose-dependent manner within minutes in male C57BL/6 mice[3].

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