Isocarboxazid
CAS No. : 59-63-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $215 | In-stock |
| 50mg | $315 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-13929 |
| M.Wt: | 231.25 |
| Formula: | C12H13N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro[1].
IC50 & Target: IC50: 4.8 μM (rat brain monoamine oxidase)[1].
In Vivo: Isocarboxazid (1, 3 mg/kg, i.p., 60 min) pretreatment in mice shows the significant increased number of head twitches at 15 and 30 min after 5-HTP[2].
Isocarboxazid (1, 3 mg/kg, i.p., 60 min) treatment in mice together with 5-HTP administration causes 43% 5-HT concentration increased and 22% of 5-HIAA decreased compared to brain concentrations in mice given 5-HTP alone[2].
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