Procaine
CAS No. : 59-46-1
| Size | Price | Stock |
|---|---|---|
| 25g | $8 | In-stock |
| 100g | $23 | In-stock |
| 500g | $115 | In-stock |
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| Cat. No. : | HY-B0546 |
| M.Wt: | 236.31 |
| Formula: | C13H20N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C) |
Procaine is a DNA-demethylating agent. Procaine acts through multiple targets and has a slow onset and a short duration of action[1][2]. In Vitro: Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM[1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest[2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale[3].
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