5-BrdU
CAS No. : 59-14-3
(Synonyms: BrdU; 5-Bromo-2'-deoxyuridine; BUdR)
| Size | Price | Stock |
|---|---|---|
| 1g | $18 | In-stock |
| 5g | $54 | In-stock |
| 10g | $98 | In-stock |
| 25g | $202 | In-stock |
| 100g | $710 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-15910 |
| M.Wt: | 307.10 |
| Formula: | C9H11BrN2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic);H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C) |
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells. In Vitro: Bromodeoxyuridine induces a progressive, dose-responsive suppression of cancer cell line and cancer stem cell population expansion RG2 rat glioma cells. In H9 cells and BJ fibroblasts, bromodeoxyuridine alters the cell cycle profile[1]. BrdU is stably integrated into the DNA, and thus can be used in assessment of cell proliferation and other cell procession[2]. In Vivo: Bromodeoxyuridine (300 mg/kg, i.p. or 0.8 mg/mL, p.o.) significantly slows tumor progression in rat glioma RG2 tumor model[1].
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