Kanamycin
CAS No. : 59-01-8
(Synonyms: Kanamycin A)
| Size | Price | Stock |
|---|---|---|
| 100mg | $30 | In-stock |
| 200mg | $50 | In-stock |
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| 1 g | Get quote | |
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| Cat. No. : | HY-16566 |
| M.Wt: | 484.50 |
| Formula: | C18H36N4O11 |
| Purity: | >98 % |
| Solubility: | H2O : 70 mg/mL (ultrasonic;warming;heat to 60°C) |
Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].
In Vitro: Kanamycin (0.1-100 μg/mL; 2 weeks) exhibits good antibacterial activity (MIC=1-5 μg/mL) to various strains of mycobacteria in vitro[1].
In Vivo: Kanamycin (2, 4 mg/kg; s.c.; once daily, 6 times a week for 3 weeks) inhibits growth of bovine tubercle bacilli in lung and spleen of mice[1].
Kanamycin (1.25, 5 mg/kg; s.c.; single (at 3 h after infection)) inhibits the multiplication of K. pneumonia DT-S in lung, trachea, and blood of mice and in proportion to the dose administration, and also increases the survival rate of mice[2].
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