Arjungenin
CAS No. : 58880-25-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $240 | In-stock |
| 10mg | $390 | In-stock |
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| Cat. No. : | HY-N4294 |
| M.Wt: | 504.70 |
| Formula: | C30H48O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV)[1][2][3][4].
In Vitro:Arjungenin (100-500 μg/g diet, 72 h) exhibits FD50 (50% refusal concentration) and GI50 (50% growth inhibition concentration) of 287.1 μg/g diet and 188.5 μg/g diet against Spilarctia obliqua[1].
Arjungenin exhibits moderate free radical scavenging activity with an IC50 value of 290.6 μg/mL and exhibits inhibitory activity against the production of hypochlorous acid[2].
Arjungenin (50 μM, 8 d) significantly promotes adipogenesis in 3T3-L1 cells by activating the FXR signaling pathway, stimulates the secretion of adiponectin and leptin by adipocytes, and improves insulin sensitivity and energy metabolism[3].
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