H-Val-Pro-Pro-OH


CAS No. : 58872-39-2

58872-39-2
Price and Availability of CAS No. : 58872-39-2
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5mg $50 In-stock
10mg $70 In-stock
25mg $120 In-stock
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Cat. No. : HY-114161
M.Wt: 311.38
Formula: C15H25N3O4
Purity: >98 %
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 58872-39-2 :

H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. IC50 & Target: IC50: 9 μM (ACE)[1]. In Vitro: H-Val-Pro-Pro-OH, a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM[1]. H-Val-Pro-Pro-OH could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes[2].

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