Nomegestrol


CAS No. : 58691-88-6

58691-88-6
Price and Availability of CAS No. : 58691-88-6
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Cat. No. : HY-105634
M.Wt: 328.45
Formula: C21H28O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 58691-88-6 :

Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. IC50 & Target: Kd: 5.44 nM (Rat uterine progesterone receptor)[1] In Vitro: Nomegestrol is a progestin, has high binding affinity at progesterone receptor, with a Kd of 5.44 nM for rat uterine progesterone receptor[1]. Nomegestrol acetate (NOMAC) is a higly selective progesterone receptor full agonist, but shows no or little binding affinity at other steroid receptors, such as the androgen and glucocorticoid receptors. Nomegestrol acetate has moderate antiandrogenic activity and strong antiestrogenic activity[2].

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