Azelastine
CAS No. : 58581-89-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $48 | In-stock |
| 25mg | $96 | In-stock |
| 50mg | $145 | In-stock |
| 100mg | $220 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-B0462A |
| M.Wt: | 381.90 |
| Formula: | C22H24ClN3O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4].
In Vitro: Azelastine can significantly inhibit HNEpC proliferation, and therefore, be helpful in against airway remodeling[5].
In Vivo: Azelastine (4 mg/kg; p.o.; daily; for 8 weeks) significantly reduces blood glucose, HbA1c and serum alkaline phosphatase (ALP), osteocalcin and downregulates apolipoprotein B in diabetic hyperlipidemic rats model[2].
Azelastine (4 mg/kg; p.o.; daily; for 8 weeks) improves the lipid profile (LDL-c decrease and HDL-c increase) in diabetic hyperlipidemic rats model[2].
Azelastine (4 mg/kg; p.o.; daily; for 8 weeks) attenuates calcium deposition and aortic calcification in diabetic hyperlipidemic rats model[2].
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