ICA-069673
CAS No. : 582323-16-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $84 | In-stock |
| 10mg | $144 | In-stock |
| 25mg | $312 | In-stock |
| 50mg | $552 | In-stock |
| 100mg | $984 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101396 |
| M.Wt: | 269.63 |
| Formula: | C11H6ClF2N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
ICA-069673 is a KCNQ2/Q3 potassium channel activator. ICA-069673 demonstrates greater selectivity for KV7.2/7.3 over KV7.3/KV7.5, with EC50s of 0.69 μM and 14.3 μM, respectively. ICA-069673 inhibits spontaneous phasic and nerve-evoked contractions in guinea pig detrusor smooth muscle (DSM). ICA-069673 also decreases the global intracellular Ca(2+) concentration in DSM cells[1][2].
IC50 & Target:IC50: 0.69 μM (KV7.2/7.3), 14.3 μM (KV7.3/7.5)[1]
In Vitro: ICA-069673 (100 nM-30 μM) dose-dependently inhibits spontaneous phasic contraction, pharmacologically induced contraction, and 10 Hz EFS induced nerve-evoked contraction, in guinea pig DSM isolated strips[1].
ICA-069673 (3 μM, 10 μM) inhibits 20 mM KCl induced DSM tonic contractions in guinea pig DSM isolated strips[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- ICA-069673
- Cat. No.:
- HY-101396
- Quantity:
Your information is safe with us.