Clavulanic acid
CAS No. : 58001-44-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $32 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $70 | In-stock |
| 50mg | $90 | In-stock |
| 100mg | $160 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-A0256 |
| M.Wt: | 199.16 |
| Formula: | C8H9NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 13.89 mg/mL (ultrasonic;warming;heat to 60°C) |
Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].
In Vitro:Clavulanic acid shows a synergistic antibacterial action (against β-lactamase-producing organisms) with Ampicillin[2].
Clavulanic acid inhibits Ab11 and Ab51 strain with MICs of 2-8 μg/mL[3].
In Vivo:Clavulanic acid (13 mg/kg, i.p.) decreases the bacterial load in the lung of an A. baumannii infected C57BL/6 mice pneumonia model[3].
Clavulanic acid (13 mg/kg, i.p.) shows a t1/2 of 6.69 h, AUC of 4.03 mg·h/L in Ab51 infected C57BL/6 mice pneumonia model[3].
Clavulanic acid (100-300 mg/kg, i.p.) shows anti-inflammatory effects on Carrageenan (HY-125474)-induced paw edema rats model[4].
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