Uridine
CAS No. : 58-96-8
(Synonyms: β-Uridine)
| Size | Price | Stock |
|---|---|---|
| 10g | $11 | In-stock |
| 25g | $14 | In-stock |
| 100g | $45 | In-stock |
| 500g | $117 | In-stock |
| 1000g | $232 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-B1449 |
| M.Wt: | 244.20 |
| Formula: | C9H12N2O6 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL;DMSO : 50 mg/mL (ultrasonic) |
Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond[1].
In Vitro:Uridine (6-24 mM, 7 days) inhibits the proliferation of leukemia cell HL-60, arrests the cell cycle at G2/M phase, and induces the differentiation of HL-60 into mature cells with characteristics of monocytes and granulocytes[1].
In Vivo:Uridine (10-20 mg/kg, oral, 6 weeks) alleviates CCl4 (HY-Y0298)-induced liver fibrosis, inhibits the expression of pro-inflammatory cytokines and the activation of the NF-κB signaling pathway in mouse liver fibrosis models[2].
Uridine (30 mg/kg, iv, single dose) exhibits anti-ischemic, antixoxidant and anti-arrhythmic effcts in rats models, exhibits protective efficacy against acute myocardial ischemia and ischemia/reperfusion injury[3].
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