Tetrabenazine (Standard)
CAS No. : 58-46-8
(Synonyms: Ro 1-9569 (Standard))
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| Cat. No. : | HY-B0590R |
| M.Wt: | 317.43 |
| Formula: | C19H27NO3 |
| Purity: | >98 % |
| Solubility: |
Tetrabenazine (Standard) is the analytical standard of Tetrabenazine (HY-B0590). This product is intended for research and analytical applications. Tetrabenazine (Ro 1-9569) is a brain-penetrant and orally active VMAT2-selective ligand with human VMAT2 Ki 100 nM. Tetrabenazine binds VMAT2 to block monoamine uptake into synaptic vesicles, potentiates cytoplasmic monoamine degradation. Tetrabenazine weakly blocks dopamine D2 receptors, and increases dopamine turnover via elevated cerebrospinal fluid homovanillic acid. Tetrabenazine can be used for the research of Huntington’s disease, tardive dyskinesia, and Tourette’s syndrome[1][2][3].
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