Centhaquin
CAS No. : 57961-90-7
(Synonyms: Centhaquine; PMZ-2010)
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $116 | In-stock |
| 25mg | $232 | In-stock |
| 50mg | $359 | In-stock |
| 100mg | $550 | In-stock |
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| Cat. No. : | HY-106690 |
| M.Wt: | 331.45 |
| Formula: | C22H25N3 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic) |
Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of? haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce?systemic vascular resistance in haemorrhagic models[1][2]. In Vivo: Centhaquine (Centhaquin) (intravenous?injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner[1]. Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci[1]. Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of?catecholamines, improving both the macro- and?microcirculation?during CPR[2].
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