Orvepitant


CAS No. : 579475-18-6

(Synonyms: GW823296)

579475-18-6
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Cat. No. : HY-122347
M.Wt: 628.62
Formula: C31H35F7N4O2
Purity: >98 %
Solubility:
Introduction of 579475-18-6 :

Orvepitant (GW823296) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant can across the blood-brain barrier. Orvepitant has the potential for depressive disorder and chronic refractory cough (CRC) treatment[1][2].

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