Diloxanide
CAS No. : 579-38-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $36 | In-stock |
| 10mg | $50 | In-stock |
| 50mg | $100 | In-stock |
| 100mg | $170 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-119972 |
| M.Wt: | 234.08 |
| Formula: | C9H9Cl2NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate (HY-B1147)[1]. In Vivo: Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate[1].Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats[2].
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