1-Phenylpropane-1,2-dione


CAS No. : 579-07-7

579-07-7
Price and Availability of CAS No. : 579-07-7
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10g $26 In-stock
25g $32 In-stock
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Cat. No. : HY-W018758
M.Wt: 148.16
Formula: C9H8O2
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 579-07-7 :

1-Phenylpropane-1,2-dione is a SARS-CoV-2 helicase binder. 1-Phenylpropane-1,2-dione can be isolated from the young stems of Ephedra sinica. 1-Phenylpropane-1,2-dione is commonly used as an edible flavoring and a basic raw material in synthetic chemistry. 1-Phenylpropane-1,2-dione can be applied to research related to COVID-19[1][2]. In Vitro: 1-Phenylpropane-1,2-dione binds to SARS-CoV-2 helicase (PDB ID: 5RMM) with a binding affinity of −11.07 kcal/mol, forming hydrogen bonds with SER486, ASN516, and ASN177 and a hydrophobic interaction with HIS554[1].

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