Cardionogen-2
CAS No. : 578755-52-9
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| Cat. No. : | HY-115474 |
| M.Wt: | 339.37 |
| Formula: | C16H13N5O2S |
| Purity: | >98 % |
| Solubility: |
Cardionogen-2 is a biphasic modulator of cardiogenesis, either promoting or inhibiting heart formation depending on the stage of treatment. Cardionogen-2 inhibits Wnt/β-catenin-dependent transcription in murine embryonic stem (ES) cells and zebrafish embryos[1]. In Vitro:In zebrafish embryos and murine embryonic stem (ES) cells, Cardionogen-2 treatment promotes cardiogenesis during and after gastrulation, whereas it inhibits heart formation before gastrulation. Cardionogen-2-induced effects can be antagonized by increasing Wnt/β-catenin signaling activity. Cardionogen-2 inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos[1].
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