Stevioside
CAS No. : 57817-89-7
| Size | Price | Stock |
|---|---|---|
| 10mg | $25 | In-stock |
| 25mg | $45 | In-stock |
| 50mg | $65 | In-stock |
| 100mg | $95 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-N0669 |
| M.Wt: | 804.87 |
| Formula: | C38H60O18 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C) |
Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities[1][2].
In Vitro:Stevioside (10 μM, 24-48 h) can enhance cytotoxicity of 5-Fluorouracil (5-Fu, HY-90006) to MDA-MB-231 and SKBR3cells[1].
Stevioside (10 μM, 48 h) combinated with 5-Fu (HY-90006) could increase the ratio of Bax to Bcl-2 in MDA-MB-231 cells, thereby triggering apoptosis[1].
Stevioside (10-1000 μM, 6 h) induces TNF-α and IL-1β release in THP-1 cells[2].
In Vivo:Stevioside (20 mg/kg, p.o., daily, 10 days) prevents significant increase in glycaemia in NMRI Haan mice[3].
Stevioside (50-200 mg/kg, i.v., one time) reduces blood pressure in a dose-dependent manner in spontaneously hypertensive rats[4].
Stevioside (6.25-25 mg/kg, p.o., daily, 15 days) increases the proliferative response of in LPS stimulated B-lymphocytes in Balb/c mice[5].
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