Carpachromene


CAS No. : 57498-96-1

57498-96-1
Price and Availability of CAS No. : 57498-96-1
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1mg $338 In-stock
5mg $845 In-stock
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Cat. No. : HY-N3542
M.Wt: 336.34
Formula: C20H16O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 57498-96-1 :

Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1]. In Vitro: Carpachromene (0-100 μg/mL, 48 h) exhibits cytotoxicity against HepG2, HepG2/IRM, PLC/PRF/5 and Raji cancer cell lines[1].
Carpachromene (20 μg/mL) significantly increases the protein expression ratios of IR, IRS1, PI3K, Akt, GSK3, and FoxO1 in HepG2/IRM cells[1].
Carpachromene (20 μg/mL) improves cellular glycogen synthesis in HepG2/IRM cells[1].

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