Fraxetin
CAS No. : 574-84-5
| Size | Price | Stock |
|---|---|---|
| 100mg | $53 | In-stock |
| 250mg | $90 | In-stock |
| 1g | $220 | In-stock |
| 5g | $770 | In-stock |
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| 50 g | Get quote | |
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| Cat. No. : | HY-N0580 |
| M.Wt: | 208.17 |
| Formula: | C10H8O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Fraxetin is isolated from Fraxinus rhynchophylla Hance and has oral bioactivity. Fraxetin has anti-tumor, antibacterial, antioxidant, and anti-inflammatory effects. Fraxetin can induce cell apoptosis[1][2][3].
In Vitro:Fraxetin (20-60 μM, 24 h) inhibits the proliferation of MCF-7 cells and induces apoptosis[1].
Fraxetin (0.02-0.08 mg/ml, 30 min) disrupts the synthesis of nucleic acids and proteins by preventing topoisomerase from binding to DNA, showing significant inhibitory effects on the proliferation of Staphylococcus aureus[2].
In Vivo:Fraxetin (20-50 mg/kg, gavage, once daily, 24 weeks) has a hepatoprotective effect in mice and also has antioxidant and anti-inflammatory activities[3].
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